Q4: 2026-02-12 Earnings Summary
EPS of -$2.23 misses by $0.23
| Revenue of $34.08M (11.58% Y/Y) beats by $919.00K
Karyopharm Therapeutics Inc. (KPTI) Q4 2025 Earnings Call February 12, 2026 8:00 AM EST
Company Participants
Brendan Strong – Senior Vice President of Investor Relations
Richard Paulson – President, CEO & Director
Reshma Rangwala – Executive VP, Chief Medical Officer & Head of Research
Sohanya Cheng – Executive VP, Chief Commercial Officer & Head of Business Development
Lori Macomber – EVP, CFO & Treasurer
Conference Call Participants
Colleen Hanley – Robert W. Baird & Co. Incorporated, Research Division
Ioannis Souroutzidis – Cantor Fitzgerald & Co., Research Division
Brian Abrahams – RBC Capital Markets, Research Division
Maurice Raycroft – Jefferies LLC, Research Division
Jonathan Chang – Leerink Partners LLC, Research Division
Presentation
Operator
Good morning. My name is Ludy, and I will be your conference operator today. At this time, I would like to welcome everyone to the Karyopharm Therapeutics Fourth Quarter and Full Year 2025 Financial Results Conference Call. [Operator Instructions] Please be advised that this call is being recorded at the company’s request.
I would now like to turn the call over to Brendan Strong, Senior Vice President, Investor Relations. Please go ahead.
Brendan Strong
Senior Vice President of Investor Relations
Good morning, and thank you all for joining us on today’s conference call to discuss Karyopharm’s fourth quarter and full year 2025 financial results and recent company progress. We issued a press release this morning detailing our financial results for the fourth quarter and full year 2025. This release, along with a slide presentation that we will reference during our call today, are available on our website.
For today’s call, as seen on Slide 2, I’m joined by Richard, Reshma, Sohanya and Lori, who will provide an update on our results for the fourth quarter and full year of 2025 and discuss recent clinical developments.
Before we begin our formal comments, I’ll remind you that
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